Microsoft(R) Windows(R) XP or Windows Vista(R) (Windows 95/98/ME/2000 are unsupported)
Microsoft DirectX(R) 9.0c (included & required for Windows XP & Vista)
CPU: Intel(R) Pentium(R) 4 3.2 GHz or AMD Athlon(TM) 64 3400+ processor
RAM: 1GB RAM
Video Card: 256MB NVIDIA(R) Geforce(R) 6800 GT or ATI Radeon(TM) X800
Sound Card: 100% DirectX 9.0c compatible sound card
HDD Space: 8GB (Plus an additional 800MB for Windows swap file)
Media: 100% Microsoft Windows compatible DVD-ROM drive
Internet: Broadband connection and service required for multiplayer
These are just the minimal system requirements, we aren't sure what the recommend requires are going to be yet, but at least this gives you a ruff estimate.
Wolfenstein is in development for the PS3, PC and Xbox 360.