There is no remake of Resident Evil 2, which was originally released on PC, in the works, but that could change if fans demand it.
According to Capcom producer Yoshiaki Hirabayashi, "Just to lay all the cards on the table, that way there's no rumor-mongering or things like that, no, we are not working on a Resident Evil 2 remake as of now. But if the fans really clamor for it; if there's a groundswell of support for remaking that game, then I think that's something Capcom would take under consideration."
Capcom last released an update for the game in 2002 for GameCube and later Windows XP.