The date '24.06.1459' is sequenced meaning we have a time for Desmond in the Animus it would appear. The new Assassin's Creed is expected this year.
The Hagia Sophia building is seen in the background of the new trailer, which is in Istanbul. The city was once known as Constantinople and was held by the Byzantine Empire but fell in 1453 to the Ottoman Empire and was renamed Istanbul - Turkish rule began.
Below is the third teaser trailer.