Microsoft Home & Entertainment Division Chief Takashi Sensui and Microsoft Game Studio Corporate Vice President Phil Spencer will be there.
The two big bosses will be giving a keynote titled 'Xbox 360's Vision and 2010's Strategy'. It will begin the very first business day of 2010's Tokyo Game Show. Last year it was Sony who started things off with CEO Kaz Hirai. A second keynote takes place afterward.
Trivia: It was at a TGS keynote speech that Nintendo first unveiled the Wiimote.