Secret Wars has been trademarked as a videogame by Marvel, strongly hinting at a game based on the famous cross-issue storyline, best known for introducing the black symbiote costume worn by Spider-Man that later became the basis for Venom.
According to Siliconera: "Marvel recently filed a trademark for 'Secret Wars' in relation to videogame products. The trademark covers everything from software to game media like cartridges to specialized hardware to sunglasses."
The most logical assumption will be that it'll be the plotline for Marvel Ultimate Alliance 3, which followed the Secret War (note the lack of an "s") and Civil War story arcs.
Let us know how much you'd love seeing a game based on Secret Wars.