Mew-Genics is the "crazy cat lady simulator" announced by Super Meat Boy developer Team Meat back in 2012 but was cancelled. Now Meat Boy and Binding of Isaac creator Edward McMillen has joined with The End Is Nigh developer Tyler Glacial to continue work on the game.
Edward McMillen announced the resurrection of Mew-Genics on his recent blog. He'll be working with Tyler Glacial once again, as they did on The End Is Nigh. Here's what he said:
"For those that don't know, Mew-genics was that cat game i worked on years ago that never saw the light of day... Welllll Tyler and I are currently prototyping some stuff for it and if all goes well I’m 99% sure that little monster will once again become my obsession. Mew-genics was always my oddball dream project and probably the game I’m questioned about the most these days. Mew-genics is being remade from the ground up so don’t expect to see much for a year or two.... Who am I kidding I’ll probably start teasing the first beta images once things get moving along…"
If you haven't played Super Meat Boy, The Binding Of Isaac or The End Is Nigh - and they're all quirky and excellent, you should -
check out the original trailer for Mew-Genics if you want to see why you should care about it. It's the greatest and catchiest trailer ever made.
The next game from the pair is The Legend of Bum-bo, described on the blog as "a mix of Puzzle Quest and The Binding of Isaac, with a tactics spin, and is technically a prequel to the Binding of Isaac." He does suggest that a sequel to Binding of Isaac is unlikely though: " truth be told, I tend to design sequels to projects I love pretty soon after release, sometimes those turn into totally new IPs, sometimes the ideas die and other times you get diarrhea. What does this mean for Isaac 2? I have no idea, but please leave me alone."