BG3's Formula Gruna can be obtained (as a Mysterious Potion) from an NPC named Araj Oblodra. You first encounter her in Act 2, at Moonrise Towers, where she'll have a relatively unusual request that involves your blood. If you choose to help her in her then-mysterious efforts, you'll meet her again in Act 3, as you descend upon Baldur's Gate proper.
Baldur's Gate 3 Formula Gruna
The second time you meet Araj, she'll ask you to drink BG3's Formula Gruna which, if you agree, she'll hand you under the guise of a Mysterious Potion. While it might be tempting to chug it without thinking, you'll want to carefully consider the implications of doing so.
Formula Gruna grants the Unstable Blood passive, making your blood highly flammable and prompting to it explode when it comes in contact with fire.
Although the explosions don't seem to count among the more damaging effects in the game, they can and will set off fires around you whenever you're fighting near flammable objects or puddles.
You get to preview the effects as you approach Araj's home, before she asks you to drink the Mysterious Potion.
Although Larian Studios dialed back the elemental shenanigans in BG3, at least when compared to Divinity: Original Sin 2, having explosions spontaneously causing fires while in the midst of a tough combat encounter can be a double-edged sword.
On the one hand, it may prove useful at dealing extra damage to foes and blocking off certain areas. At the same time, if you party isn't resistant to fire and particularly mobile, you can end up giving your enemy the upper hand.
Whether or not you should drink Baldur's Gate 3's Formula Gruna is ultimately up to you, depending on how risky a playstyle you want to attempt during your playthrough.
If your party can mitigate fire damage well enough, it could prove to be another useful tool in your arsenal.
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