As large-scale MMO-ish releases often do when they're still young, Defiance 2050 does have a few issues that the developer, Trion Worlds, is intent on tackling head-on, with their very first hotfix having been released not two days after the game's official release.
Due to the nature of the hotfix, which included server optimisations to hopefully alleviate server latency issues, as well as due to the game's infrastructure, there was downtime scheduled so that the hotfix could be applied properly. Downtime for all platforms and regions started at 07:45 PT/10:35 ET/14:45 GMT/15:45 BST, and lasted for approximately 30 to 45 minutes.
Defiance 2050 Hotfix 7/10/2018 patch notes
Following is the complete list of fixes as per the upcoming Defiance hotfix.
Also worth mentioning is the update from the day before, which boasted its own list of fixes and improvements.
Defiance 2050 Hotfix 7/9/2018 patch notes