First seen on LV-895 in the original game, Pathogen Runners are Xenomorph Runners infected and mutated by the black goo. A single Pathogen Runner is a low-threat enemy in Aliens: Fireteam Elite 2, but like its usual Xeno counterpart, it usually attacks alongside tens – if not hundreds – of its friends.
When it comes to their appearance, Pathogen Runners actually resemble Xeno Spitters even if their tactics mostly boil down to overwhelming Colonial Marine squads with numbers and regular melee attacks. Like most Pathogen-mutated foes, they're resilient and hostile to all other organisms, including Xenomorphs.
There's no special way of dealing with Pathogen Runners. While they can resist more damage than regular Runners, most of the weaponry available to Marine squads will eliminate them quickly. Just don't let them overwhelm you or distract from bigger threats.

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